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2004-11-11

High life

Now we know why chubby people are always cheery. They are naturally high:

Rimonabant works by blocking a receptor called CB1, which is bound to by compounds called cannabinoids. These are produced both naturally in the body and in plants such as cannabis. The receptor is present on the surfaces of many cells throughout the body, including fat cells and those in the hypothalamus, the brain region that is thought to determine appetite (hence the famous ‘munchies’ experienced by cannabis smokers).

Drug eases cravings for food and cigarettes

07:01

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